This anti-aging cream was _________________ Clarissa.

The choice "highly recommended to me by" is correct because it conveys a strong endorsement or approval from someone about the anti-aging cream, indicating that Clarissa is the source of that recommendation. This phrase effectively communicates that someone, presumably Clarissa, has advised others to use the cream, suggesting it is perceived positively and reliably.

When we look at the other options, "frequently discussed by" suggests a general conversation about the cream rather than a personal recommendation. It implies that people talk about it often, but not necessarily in a positive or directive manner. "Often suggested by" also indicates that the cream is mentioned to others, but lacks the stronger connotation of enthusiasm or trust that "highly recommended" provides. Finally, "noted for its quality by" focuses on the cream's quality rather than the action of a recommendation, which doesn’t fit the context of personal advice from Clarissa.

Therefore, "highly recommended to me by" captures the intent of expressing strong approval and personal advocacy, making it the best fit for the sentence.